Ventilator-Dependent Patients With no Respiratory Illnesses in an Intermediate Care Unit are Successfully Supported by a Resuscitator Bag-Based Mechanical Ventilator

The latest pandemic showed evidence of an urgent need for innovation in mechanical ventilation strategies worldwide to meet ever-increasing scenarios where life support is needed. Here we show first-in-human data of a novel type of mechanical ventilator based on automating a resuscitation bag called Masi that can effectively work in an intermediate care unit. Blood biochemistry levels and other variables during mechanical ventilation with Masi were comparable to the values obtained when the patients were supported by a conventional mechanical ventilator. It was verified that the levels of blood oxygenation of the patients was not different between commercial or Masi ventilators. Also, the treating physician reported no incidents or clinical observations of concern while Masi was being used. Therefore, we conclude that Masi successfully provides life support to ventilator-dependent patients with no respiratory illnesses within an intermediate care environment.