Prostate cancer detection using crawling wave sonoelastography

Benjamin Castaneda, Liwei An, Shuang Wu, Laurie L. Baxter, Jorge L. Yao, Jean V. Joseph, Kenneth Hoyt, John Strang, Deborah J. Rubens, Kevin J. Parker

Producción científica: Capítulo del libro/informe/acta de congresoContribución a la conferenciarevisión exhaustiva

30 Citas (Scopus)


Crawling wave (CrW) sonoelastography is an elasticity imaging technique capable of estimating the localized shear wave speed in tissue and, therefore, can provide a quantitative estimation of the Young's modulus for a given vibration frequency. In this paper, this technique is used to detect cancer in excised human prostates and to provide quantitative estimations of the viscoelastic properties of cancerous and normal tissues. Image processing techniques are introduced to compensate for attenuation and reflection artifacts of the CrW images. Preliminary results were obtained with fifteen prostate glands after radical prostatectomy. The glands were vibrated at 100, 120 and 140Hz. At each frequency, three cross-sections of the gland (apex, mid-gland and base) were imaged using CrW Sonoelastography and compared to corresponding histological slices. Results showed good spatial correspondence with histology and an 80% accuracy in cancer detection. In addition, shear velocities for cancerous and normal tissues were estimated as 4.75±0.97 m/s and 3.26±0.87 m/s, respectively.

Idioma originalInglés
Título de la publicación alojadaMedical Imaging 2009
Subtítulo de la publicación alojadaUltrasonic Imaging and Signal Processing
EstadoPublicada - 2009
EventoMedical Imaging 2009: Ultrasonic Imaging and Signal Processing - Lake Buena Vista, FL, Estados Unidos
Duración: 8 feb. 20099 feb. 2009

Serie de la publicación

NombreProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (versión impresa)1605-7422


ConferenciaMedical Imaging 2009: Ultrasonic Imaging and Signal Processing
País/TerritorioEstados Unidos
CiudadLake Buena Vista, FL


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