In vivo attenuation estimation in human thyroid nodules using the regularized spectral log difference technique: Initial pilot study

Andres Coila, Rosa Laimes, Claudia Salazar, Julien Rouyer, Gabriel Jimenez, Joseph A. Pinto, Jorge Guerrero, Roberto Lavarello

Producción científica: Capítulo del libro/informe/acta de congresoContribución a la conferenciarevisión exhaustiva

7 Citas (Scopus)

Resumen

In vivo estimation of attenuation coefficients is useful because of its potential for tissue characterization and relevance in accurate backscatter coefficient estimation. Recently, the regularized spectral log difference (RSLD) technique was proposed to extend the trade-off between precision and spatial resolution in attenuation coefficient slope (ACS) estimation. The aim of this pilot study is to validate the feasibility of in vivo estimation of ACSs from thyroid nodules using the RSLD technique. In vivo data from thyroid nodules was acquired in an oncology clinic right before fine needle aspiration biopsy (FNAB) procedure. Six nodules were analyzed in this study having FNAB results reported as either Bethesda II (benign) or VI (cancer). The nodules had an average diameter of 1.56 cm and their biopsy results were adenomatoid nodules (three cases), Hashimoto's thyroiditis (two cases), and papillary carcinoma (one case). In addition, healthy thyroid regions in three additional patients were also evaluated. The ACS estimation was performed with 16 wavelength axially by 16 wavelengths laterally data blocks. The average ACS values in healthy thyroid tissues and Hashimoto's thyroiditis nodules were found to be 1.62 ± 0.27 and 0.97 ± 0.08 dB.cm-1.MHz-1, which are consistent with previous reports in this subject in the literature. The ACS values for the adenomatoid nodules and the papillary carcinoma were 0.94 ± 0.07 and 0.87 dB.cm-1.MHz-1, respectively. All nodules had lower ACS values than the ones in healthy thyroid tissues. These results suggest that the RSLD method has potential for producing accurate and precise estimates of ACS values in vivo.

Idioma originalInglés
Título de la publicación alojada2017 IEEE International Ultrasonics Symposium, IUS 2017
EditorialIEEE Computer Society
ISBN (versión digital)9781538633830
DOI
EstadoPublicada - 31 oct. 2017
Evento2017 IEEE International Ultrasonics Symposium, IUS 2017 - Washington, Estados Unidos
Duración: 6 set. 20179 set. 2017

Serie de la publicación

NombreIEEE International Ultrasonics Symposium, IUS
ISSN (versión impresa)1948-5719
ISSN (versión digital)1948-5727

Conferencia

Conferencia2017 IEEE International Ultrasonics Symposium, IUS 2017
País/TerritorioEstados Unidos
CiudadWashington
Período6/09/179/09/17

Huella

Profundice en los temas de investigación de 'In vivo attenuation estimation in human thyroid nodules using the regularized spectral log difference technique: Initial pilot study'. En conjunto forman una huella única.

Citar esto