TY - JOUR
T1 - HUMAN SPACE MEDICINE
T2 - PHYSIOLOGICAL PERFORMANCE and COUNTERMEASURES to IMPROVE the ASTRONAUT'S HEALTH
AU - Rivera, Milton V.
AU - Cornejo, José
AU - Huallpayunca, Karen
AU - Diaz, Aurora B.
AU - Ortiz-Benique, Zhamanda N.
AU - Reina, Andrés D.
AU - Lino, Gustavo Jamanca
AU - Ticllacuri, Victor
N1 - Publisher Copyright:
Copyright Mishina ES et al.
PY - 2020/6/1
Y1 - 2020/6/1
N2 - This Review Article is presented based on current scientific evidence on space medicine focused on human physiology and its countermeasures. Therefore, a non-systematic bibliographic search of scientific articles and research books in English-Spanish of the last 7 years was carried out, detailing their application in humans, murine models and in vitro experiments. The conditions of the space environment such as microgravity and radiation that produce considerable physiological changes in the cardiovascular system (redistribution of fluids, cardiovascular remodeling, arrhythmias) were taken into account; nervous (sensorimotor, neurosensory, neurovestibular); respiratory (volume and capacity changes); renal (lithiasis); musculoskeletal (muscular atrophy, osteoporosis); hematological (anemia); immunological (immune dysregulation) and digestive (intestinal microbiota disorder). In addition, there are biological, molecular and genetic processes still to be explored, in order to know and mitigate the uncertain mechanisms triggered in extreme and dangerous environments. Therefore, it is a priority to develop and implement countermeasures to reduce the harmful effects on health, with the aim of guaranteeing the astronaut's adaptation, safety and performance during future space flights.
AB - This Review Article is presented based on current scientific evidence on space medicine focused on human physiology and its countermeasures. Therefore, a non-systematic bibliographic search of scientific articles and research books in English-Spanish of the last 7 years was carried out, detailing their application in humans, murine models and in vitro experiments. The conditions of the space environment such as microgravity and radiation that produce considerable physiological changes in the cardiovascular system (redistribution of fluids, cardiovascular remodeling, arrhythmias) were taken into account; nervous (sensorimotor, neurosensory, neurovestibular); respiratory (volume and capacity changes); renal (lithiasis); musculoskeletal (muscular atrophy, osteoporosis); hematological (anemia); immunological (immune dysregulation) and digestive (intestinal microbiota disorder). In addition, there are biological, molecular and genetic processes still to be explored, in order to know and mitigate the uncertain mechanisms triggered in extreme and dangerous environments. Therefore, it is a priority to develop and implement countermeasures to reduce the harmful effects on health, with the aim of guaranteeing the astronaut's adaptation, safety and performance during future space flights.
KW - Adaptation
KW - Astronaut (source: MeSH NLM)
KW - Countermeasures
KW - Health
KW - Human physiology
KW - Microgravity
KW - Performance
KW - Radiation
KW - Safety
KW - Space medicine
UR - http://www.scopus.com/inward/record.url?scp=85196764724&partnerID=8YFLogxK
U2 - 10.25176/RFMH.v20i2.2920
DO - 10.25176/RFMH.v20i2.2920
M3 - Article
AN - SCOPUS:85196764724
SN - 1814-5469
VL - 20
SP - 303
EP - 314
JO - Revista de la Facultad de Medicina Humana
JF - Revista de la Facultad de Medicina Humana
IS - 2
ER -