TY - JOUR
T1 - Frequency of human bocavirus (HBoV) infection among children with febrile respiratory symptoms in Argentina, Nicaragua and Peru
AU - Salmón-Mulanovich, Gabriela
AU - Sovero, Merly
AU - Laguna-Torres, V. Alberto
AU - Kochel, Tadeusz J.
AU - Lescano, Andres G.
AU - Chauca, Gloria
AU - Sanchez, J. Felix
AU - Rodriguez, Francisco
AU - Parrales, Eduardo
AU - Ocaña, Victor
AU - Barrantes, Melvin
AU - Blazes, David L.
AU - Montgomery, Joel M.
PY - 2011/1
Y1 - 2011/1
N2 - Background Globally, respiratory infections are the primary cause of illness in developing countries, specifically among children; however, an etiological agent for many of these illnesses is rarely identified.Objectives Our study aimed to estimate the frequency of human bocavirus (HBoV) infection among pediatric populations in Argentina, Nicaragua and Peru.Methods We conducted a cross-sectional study using stored samples of an influenza-like illness surveillance program. Irrespective of previous diagnosis, nasopharyngeal or nasal swab specimens were randomly selected and tested using real-time PCR from three sites during 2007 from patients younger than 6 years old.Results A total of 568 specimens from Argentina (185), Nicaragua (192) and Peru (191) were tested. The prevalence of HBoV was 10.8% (95% CI: 6.3; 15.3) in Argentina, 33.3% in Nicaragua (95% CI: 26.6; 40.1) and 25.1% in Peru (95% CI: 18.9; 31.3).Conclusions These findings demonstrate circulation of HBoV in Argentina, Nicaragua and Peru among children with influenza-like symptoms enrolled in a sentinel surveillance program.
AB - Background Globally, respiratory infections are the primary cause of illness in developing countries, specifically among children; however, an etiological agent for many of these illnesses is rarely identified.Objectives Our study aimed to estimate the frequency of human bocavirus (HBoV) infection among pediatric populations in Argentina, Nicaragua and Peru.Methods We conducted a cross-sectional study using stored samples of an influenza-like illness surveillance program. Irrespective of previous diagnosis, nasopharyngeal or nasal swab specimens were randomly selected and tested using real-time PCR from three sites during 2007 from patients younger than 6 years old.Results A total of 568 specimens from Argentina (185), Nicaragua (192) and Peru (191) were tested. The prevalence of HBoV was 10.8% (95% CI: 6.3; 15.3) in Argentina, 33.3% in Nicaragua (95% CI: 26.6; 40.1) and 25.1% in Peru (95% CI: 18.9; 31.3).Conclusions These findings demonstrate circulation of HBoV in Argentina, Nicaragua and Peru among children with influenza-like symptoms enrolled in a sentinel surveillance program.
KW - Epidemiology
KW - Human bocavirus
KW - Respiratory illness
UR - http://www.scopus.com/inward/record.url?scp=78650113663&partnerID=8YFLogxK
U2 - 10.1111/j.1750-2659.2010.00160.x
DO - 10.1111/j.1750-2659.2010.00160.x
M3 - Article
C2 - 21138534
AN - SCOPUS:78650113663
SN - 1750-2640
VL - 5
SP - 1
EP - 5
JO - Influenza and other Respiratory Viruses
JF - Influenza and other Respiratory Viruses
IS - 1
ER -
