TY - JOUR
T1 - Determination of the absolute configuration of 19-OH-(-)-eburnamonine using a combination of residual dipolar couplings, DFT chemical shift predictions, and chiroptics
AU - Trigo-Mouriño, Pablo
AU - Sifuentes, Roxana
AU - Navarro-Vázquez, Armando
AU - Gayathri, Chakicherla
AU - Maruenda, Helena
AU - Gil, Roberto R.
PY - 2012/6
Y1 - 2012/6
N2 - 19-OH-(-)-eburnamonine 1 is a new indole alkaloid isolated from Bonafusia macrocalyx. A natural derivative from (-)-eburnamonine for which absolute configuration and conformation has been determined by making use of residual dipolar couplings enhanced NMR, circular dichroism spectra and high-level computations.
AB - 19-OH-(-)-eburnamonine 1 is a new indole alkaloid isolated from Bonafusia macrocalyx. A natural derivative from (-)-eburnamonine for which absolute configuration and conformation has been determined by making use of residual dipolar couplings enhanced NMR, circular dichroism spectra and high-level computations.
KW - CD
KW - Conformational analysis
KW - DFT
KW - Indole alkaloids
KW - Natural products
KW - RDC
KW - Structural elucidation
UR - http://www.scopus.com/inward/record.url?scp=84864692376&partnerID=8YFLogxK
U2 - 10.1177/1934578x1200700611
DO - 10.1177/1934578x1200700611
M3 - Article
C2 - 22816295
AN - SCOPUS:84864692376
SN - 1934-578X
VL - 7
SP - 735
EP - 738
JO - Natural Product Communications
JF - Natural Product Communications
IS - 6
ER -