A systematic review of the utility of 1.5 versus 3 Tesla magnetic resonance brain imaging in clinical practice and research

Joanna M. Wardlaw, Will Brindle, Ana M. Casado, Kirsten Shuler, Moira Henderson, Brenda Thomas, Jennifer MacFarlane, Susana Muñoz Maniega, Katherine Lymer, Zoe Morris, Cyril Pernet, William Nailon, Trevor Ahearn, Abdul Nashirudeen Mumuni, Carlos Mugruza, John McLean, Goultchira Chakirova, Yuehui Tao, Johanna Simpson, Andrew C. StanfieldHarriet Johnston, Jehill Parikh, Natalie A. Royle, Janet De Wilde, Mark E. Bastin, Nick Weir, Andrew Farrall, Maria C.Valdes Hernandez

Producción científica: Contribución a una revistaArtículo de revisiónrevisión exhaustiva

68 Citas (Scopus)


Objective MRI at 3 T is said to be more accurate than 1.5 T MR, but costs and other practical differences mean that it is unclear which to use. Methods We systematically reviewed studies comparing diagnostic accuracy at 3 T with 1.5 T. We searched MEDLINE, EMBASE and other sources from 1 January 2000 to 22 October 2010 for studies comparing diagnostic accuracy at 1.5 and 3 T in human neuroimaging. We extracted data on methodology, quality criteria, technical factors, subjects, signal-to-noise, diagnostic accuracy and errors according to QUADAS and STARD criteria. Results Amongst 150 studies (4,500 subjects), most were tiny, compared old 1.5 T with new 3 T technology, and only 22 (15 %) described diagnostic accuracy. The 3 T images were often described as "crisper", but we found little evidence of improved diagnosis. Improvements were limited to research applications [functional MRI (fMRI), spectroscopy, automated lesion detection]. Theoretical doubling of the signal-to-noise ratio was not confirmed, mostly being 25 %. Artefacts were worse and acquisitions took slightly longer at 3 T. Conclusion Objective evidence to guide MRI purchasing decisions and routine diagnostic use is lacking. Rigorous evaluation accuracy and practicalities of diagnostic imaging technologies should be the routine, as for pharmacological interventions, to improve effectiveness of healthcare. Key Points • Higher field strength MRI may improve image quality and diagnostic accuracy. • There are few direct comparisons of 1.5 and 3 T MRI. • Theoretical doubling of the signal-to-noise ratio in practice was only 25 %. • Objective evidence of improved routine clinical diagnosis is lacking. • Other aspects of technology improved images more than field strength.

Idioma originalInglés
Páginas (desde-hasta)2295-2303
Número de páginas9
PublicaciónEuropean Radiology
EstadoPublicada - nov. 2012
Publicado de forma externa


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