Synthesis and characterization of new bi-sensitive copoly(2-oxazolines)

Juan Carlos Rueda; Miguel Asmad; Valeria Ruiz; Hartmut Komber; Stefan Zschoche; Brigitte Voit

doi:10.1080/15685551.2015.1078109

Synthesis and characterization of new bi-sensitive copoly(2-oxazolines)

Juan Carlos Rueda, Miguel Asmad, Valeria Ruiz, Hartmut Komber, Stefan Zschoche, Brigitte Voit

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15 Scopus citations

Abstract

We synthesized new bi-sensitive statistical copolymers and A-B-A triblock copolymers from 2-cyclopropyl-2-oxazoline (CPOxa) and 2-methoxycarbonylethyl-2-oxazoline (MEtOxa) using 1,4-dibromobutene as a bi-functional initiating moiety. These new bi-sensitive polymers were obtained via quasi-living polymerization of the oxazoline monomers and subsequent hydrolysis of the methyl ester of MEtOxa. Their thermal conformational transitions in aqueous solution were between 30 and 60 °C and these values were dependent of the copolymer composition, polymer structure (statistical or block copolymer), and of the pH of the solution, where the polymers were dissolved. The achieved polymers could find application in biomaterial science, in microsystems and sensors, and as smart nanocarriers.

Original language	English
Pages (from-to)	761-769
Number of pages	9
Journal	Designed Monomers and Polymers
Volume	18
Issue number	8
DOIs	https://doi.org/10.1080/15685551.2015.1078109
State	Published - 17 Nov 2015

Keywords

amphiphiles
block copolymers
living polymerization
stimuli-sensitive polymers
thermal properties
transition

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10.1080/15685551.2015.1078109

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title = "Synthesis and characterization of new bi-sensitive copoly(2-oxazolines)",

abstract = "We synthesized new bi-sensitive statistical copolymers and A-B-A triblock copolymers from 2-cyclopropyl-2-oxazoline (CPOxa) and 2-methoxycarbonylethyl-2-oxazoline (MEtOxa) using 1,4-dibromobutene as a bi-functional initiating moiety. These new bi-sensitive polymers were obtained via quasi-living polymerization of the oxazoline monomers and subsequent hydrolysis of the methyl ester of MEtOxa. Their thermal conformational transitions in aqueous solution were between 30 and 60 °C and these values were dependent of the copolymer composition, polymer structure (statistical or block copolymer), and of the pH of the solution, where the polymers were dissolved. The achieved polymers could find application in biomaterial science, in microsystems and sensors, and as smart nanocarriers.",

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T1 - Synthesis and characterization of new bi-sensitive copoly(2-oxazolines)

AU - Rueda, Juan Carlos

AU - Asmad, Miguel

AU - Ruiz, Valeria

AU - Komber, Hartmut

AU - Zschoche, Stefan

AU - Voit, Brigitte

PY - 2015/11/17

Y1 - 2015/11/17

N2 - We synthesized new bi-sensitive statistical copolymers and A-B-A triblock copolymers from 2-cyclopropyl-2-oxazoline (CPOxa) and 2-methoxycarbonylethyl-2-oxazoline (MEtOxa) using 1,4-dibromobutene as a bi-functional initiating moiety. These new bi-sensitive polymers were obtained via quasi-living polymerization of the oxazoline monomers and subsequent hydrolysis of the methyl ester of MEtOxa. Their thermal conformational transitions in aqueous solution were between 30 and 60 °C and these values were dependent of the copolymer composition, polymer structure (statistical or block copolymer), and of the pH of the solution, where the polymers were dissolved. The achieved polymers could find application in biomaterial science, in microsystems and sensors, and as smart nanocarriers.

AB - We synthesized new bi-sensitive statistical copolymers and A-B-A triblock copolymers from 2-cyclopropyl-2-oxazoline (CPOxa) and 2-methoxycarbonylethyl-2-oxazoline (MEtOxa) using 1,4-dibromobutene as a bi-functional initiating moiety. These new bi-sensitive polymers were obtained via quasi-living polymerization of the oxazoline monomers and subsequent hydrolysis of the methyl ester of MEtOxa. Their thermal conformational transitions in aqueous solution were between 30 and 60 °C and these values were dependent of the copolymer composition, polymer structure (statistical or block copolymer), and of the pH of the solution, where the polymers were dissolved. The achieved polymers could find application in biomaterial science, in microsystems and sensors, and as smart nanocarriers.

KW - amphiphiles

KW - block copolymers

KW - living polymerization

KW - stimuli-sensitive polymers

KW - thermal properties

KW - transition

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JO - Designed Monomers and Polymers

JF - Designed Monomers and Polymers

IS - 8

ER -

Synthesis and characterization of new bi-sensitive copoly(2-oxazolines)

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Keywords

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