Sodium borohydride-amberlyst-15 (H+): An effective reductor for hindered and unreactive ketones in aprotic solvent

Juana Robles Caycho, Fernando García Tellado, Pedro De Armas, José Juan Marrero Tellado

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

The combination of sodium borohydride and amberlyst-15 (H+) in tetrahydrofurane is a powerful reductor for unreactive ketones. The reduction is fast, high-yielding and the work-up is extremely simple. Ketals, silyl ethers and other organic functions are not disturbed during the reduction.

Original languageEnglish
Pages (from-to)277-280
Number of pages4
JournalTetrahedron Letters
Volume38
Issue number2
DOIs
StatePublished - 13 Jan 1997
Externally publishedYes

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