Receptors for epidermal growth factor in human mammary carcinomas and their metastases.

A. Macias, E. Azavedo, R. Perez, L. E. Rutqvist, L. Skoog

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

The tumor cell content of the receptor for epidermal growth factor (EGF-R) and estrogen receptor (ER) was analyzed in 36 primary breast carcinomas and their metastatic deposits. Twenty-five percent of the primary tumors and 48 percent of the metastases exhibited measurable levels of the receptor. The frequency of EGF-R positivity was the same for cutaneous and lymph node recurrences. No discrepancy was observed with respect to ER content between primary tumors and their metastases.

Original languageEnglish
Pages (from-to)849-851
Number of pages3
JournalAnticancer Research
Volume6
Issue number4
StatePublished - Jul 1986

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