TY - GEN
T1 - Performance of three-dimensional sonoelastography in prostate cancer detection
T2 - 2009 IEEE International Ultrasonics Symposium, IUS 2009
AU - Castaneda, B.
AU - Hoyt, K.
AU - Westesson, K.
AU - An, L.
AU - Yao, J.
AU - Baxter, L.
AU - Joseph, J.
AU - Strang, J.
AU - Rubens, D.
AU - Parker, K.
PY - 2009
Y1 - 2009
N2 - In this paper, we evaluate and compare the performance of three-dimensional (3D) sonoelastography for prostate cancer detection ex vivo and in vivo. Ultrasound (US) B-mode and sonoelastographic volumes were acquired from eleven prostate glands before and after radical prostatectomy. Semi-automatic algorithms were used to segment the surface of the gland from the US B-mode volume and the tumors from sonoelastographic data. To assess the detection performance, 3D sonoelastographic findings were compared in size and position to 3D histological data. One gland was discarded due to poor contact. In the remaining ten, both, in vivo and ex vivo sonoelastography showed similar performance in prostate cancer detection: over 80% accuracy for tumors larger than 4 mm in estimated diameter. These results are an improvement over US B-mode but not yet sufficient to replace biopsy. However, 3D sonoelastography has the potential to become an imaging tool to guide biopsies.
AB - In this paper, we evaluate and compare the performance of three-dimensional (3D) sonoelastography for prostate cancer detection ex vivo and in vivo. Ultrasound (US) B-mode and sonoelastographic volumes were acquired from eleven prostate glands before and after radical prostatectomy. Semi-automatic algorithms were used to segment the surface of the gland from the US B-mode volume and the tumors from sonoelastographic data. To assess the detection performance, 3D sonoelastographic findings were compared in size and position to 3D histological data. One gland was discarded due to poor contact. In the remaining ten, both, in vivo and ex vivo sonoelastography showed similar performance in prostate cancer detection: over 80% accuracy for tumors larger than 4 mm in estimated diameter. These results are an improvement over US B-mode but not yet sufficient to replace biopsy. However, 3D sonoelastography has the potential to become an imaging tool to guide biopsies.
KW - Elasticity imaging
KW - Prostate cancer detection
KW - Sonoelastography
KW - Three-dimensional ultrasound
UR - http://www.scopus.com/inward/record.url?scp=77952825114&partnerID=8YFLogxK
U2 - 10.1109/ULTSYM.2009.5441763
DO - 10.1109/ULTSYM.2009.5441763
M3 - Conference contribution
AN - SCOPUS:77952825114
SN - 9781424443895
T3 - Proceedings - IEEE Ultrasonics Symposium
SP - 519
EP - 522
BT - 2009 IEEE International Ultrasonics Symposium and Short Courses, IUS 2009
PB - Institute of Electrical and Electronics Engineers Inc.
Y2 - 20 September 2009 through 23 September 2009
ER -
