Microwave processing of starch-based porous structures for tissue engineering scaffolds

Fernando G. Torres, Aldo R. Boccaccini, Omar P. Troncoso

Research output: Contribution to journalArticlepeer-review

44 Scopus citations

Abstract

A novel microwave (MW) processing technique was used to produce biodegradable scaffolds for tissue engineering from different types of starch-based polymers. Potato, sweet potato, corn starch, and nonisolated amaranth and quinoa starch were used to produce porous structures. Water and glycerol were used as plasticizers for the different types of starch. Characterization of the pore morphology of the scaffolds was carried out with scanning electron microscopy. Three-dimensional structures with variable porosity and pore size distribution were obtained with the MW foaming technique. The amount of remaining water in the scaffolds and their corresponding densities showed important variations among the different types of starch. Compressive mechanical properties were assessed by indentation tests, and a strong dependence of the indentation stress on the average pore size was found. Studies in simulated body fluid were used to assess the in vitro bioactivity, degradability, and surface topology evolution in the scaffolds.

Original languageEnglish
Pages (from-to)1332-1339
Number of pages8
JournalJournal of Applied Polymer Science
Volume103
Issue number2
DOIs
StatePublished - 15 Jan 2007

Keywords

  • Biological applications of polymers
  • Biomaterials
  • Macroporous polymers

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