TY - GEN
T1 - Highly Efficient Ultrasound-Assisted Anthocyanin Extraction for Colorimetric Sensors and Drug Delivery Systems in Wound Dressings
AU - Vilcahuamán, Keliee
AU - Elgegren, Mariela
AU - Kim, Suyeon
AU - Nakamatsu, Javier
N1 - Publisher Copyright:
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2025.
PY - 2025
Y1 - 2025
N2 - Anthocyanins were extracted from Peruvian purple cabbage (PC) using ultrasonication, a greener and more efficient technique. The anthocyanin extract was incorporated into polymeric alginate membranes to obtain a pH-sensitive biosensor to monitor wound healing processes and drug delivery. The halochromic behavior was tested in five different acidic media (pH 4, 5, 6, 7, and 8) giving a differential colour for each. The antioxidant capacity of the PC extract was evaluated using the ABTS discoloration assay. A 1% (w/v) solution of the lyophilized extract resulted in 55.17 ± 0.46 TEAC mg/g. Phenolic content and equivalents of cyanidin-3-glucoside were evaluated using the Folin-Ciocalteu and pH differential assays, respectively, resulting in 36.1 ± 0.55 GAE mg and 8.63 ± 0.54 of C-3-G mg per gram of lyophilized extract, respectively. Finally, the PC extract was embedded in alginate (AL) membranes and characterized by contact angle and transparency.
AB - Anthocyanins were extracted from Peruvian purple cabbage (PC) using ultrasonication, a greener and more efficient technique. The anthocyanin extract was incorporated into polymeric alginate membranes to obtain a pH-sensitive biosensor to monitor wound healing processes and drug delivery. The halochromic behavior was tested in five different acidic media (pH 4, 5, 6, 7, and 8) giving a differential colour for each. The antioxidant capacity of the PC extract was evaluated using the ABTS discoloration assay. A 1% (w/v) solution of the lyophilized extract resulted in 55.17 ± 0.46 TEAC mg/g. Phenolic content and equivalents of cyanidin-3-glucoside were evaluated using the Folin-Ciocalteu and pH differential assays, respectively, resulting in 36.1 ± 0.55 GAE mg and 8.63 ± 0.54 of C-3-G mg per gram of lyophilized extract, respectively. Finally, the PC extract was embedded in alginate (AL) membranes and characterized by contact angle and transparency.
KW - Anthocyanin
KW - Biosensor
KW - Chronic Wounds
KW - Drug Delivery
KW - Wound Dressings
UR - https://www.scopus.com/pages/publications/105006424425
U2 - 10.1007/978-3-031-89510-4_13
DO - 10.1007/978-3-031-89510-4_13
M3 - Conference contribution
AN - SCOPUS:105006424425
SN - 9783031895098
T3 - IFMBE Proceedings
SP - 141
EP - 153
BT - 10th Latin American Congress on Biomedical Engineering - Proceedings of CLAIB 2024
A2 - Martinez-Licona, Fabiola M.
A2 - Ballarin, Virginia L.
A2 - Ibarra-Ramírez, Ernesto A.
A2 - Perez-Buitrago, Sandra M.
A2 - Berriere, Luis R.
PB - Springer Science and Business Media Deutschland GmbH
T2 - 10th Latin American Congress of Biomedical Engineering, CLAIB 2024
Y2 - 2 October 2024 through 5 October 2024
ER -