Determination of the absolute configuration of 19-OH-(-)-eburnamonine using a combination of residual dipolar couplings, DFT chemical shift predictions, and chiroptics

Pablo Trigo-Mouriño; Roxana Sifuentes; Armando Navarro-Vázquez; Chakicherla Gayathri; Helena Maruenda; Roberto R. Gil

Determination of the absolute configuration of 19-OH-(-)-eburnamonine using a combination of residual dipolar couplings, DFT chemical shift predictions, and chiroptics

Pablo Trigo-Mouriño
, Roxana Sifuentes
, Armando Navarro-Vázquez
, Chakicherla Gayathri
, Helena Maruenda
, Roberto R. Gil

Sección de Química

Universidade de Vigo
Carnegie Mellon University
Pontificia Universidad Católica del Perú

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

19-OH-(-)-eburnamonine 1 is a new indole alkaloid isolated from Bonafusia macrocalyx. A natural derivative from (-)-eburnamonine for which absolute configuration and conformation has been determined by making use of residual dipolar couplings enhanced NMR, circular dichroism spectra and high-level computations.

Original language	Spanish
Pages (from-to)	735-738
Number of pages	4
Journal	Natural Product Communications
Volume	7
State	Published - 1 Jun 2012

Cite this

@article{63abb30996d844f8981a6aac50013778,

title = "Determination of the absolute configuration of 19-OH-(-)-eburnamonine using a combination of residual dipolar couplings, DFT chemical shift predictions, and chiroptics",

abstract = "19-OH-(-)-eburnamonine 1 is a new indole alkaloid isolated from Bonafusia macrocalyx. A natural derivative from (-)-eburnamonine for which absolute configuration and conformation has been determined by making use of residual dipolar couplings enhanced NMR, circular dichroism spectra and high-level computations.",

author = "Pablo Trigo-Mouri{\~n}o and Roxana Sifuentes and Armando Navarro-V{\'a}zquez and Chakicherla Gayathri and Helena Maruenda and Gil, \{Roberto R.\}",

year = "2012",

month = jun,

day = "1",

language = "Espa{\~n}ol",

volume = "7",

pages = "735--738",

journal = "Natural Product Communications",

issn = "1934-578X",

}

Determination of the absolute configuration of 19-OH-(-)-eburnamonine using a combination of residual dipolar couplings, DFT chemical shift predictions, and chiroptics. / Trigo-Mouriño, Pablo; Sifuentes, Roxana; Navarro-Vázquez, Armando et al.
In: Natural Product Communications, Vol. 7, 01.06.2012, p. 735-738.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Determination of the absolute configuration of 19-OH-(-)-eburnamonine using a combination of residual dipolar couplings, DFT chemical shift predictions, and chiroptics

AU - Trigo-Mouriño, Pablo

AU - Sifuentes, Roxana

AU - Navarro-Vázquez, Armando

AU - Gayathri, Chakicherla

AU - Maruenda, Helena

AU - Gil, Roberto R.

PY - 2012/6/1

Y1 - 2012/6/1

N2 - 19-OH-(-)-eburnamonine 1 is a new indole alkaloid isolated from Bonafusia macrocalyx. A natural derivative from (-)-eburnamonine for which absolute configuration and conformation has been determined by making use of residual dipolar couplings enhanced NMR, circular dichroism spectra and high-level computations.

AB - 19-OH-(-)-eburnamonine 1 is a new indole alkaloid isolated from Bonafusia macrocalyx. A natural derivative from (-)-eburnamonine for which absolute configuration and conformation has been determined by making use of residual dipolar couplings enhanced NMR, circular dichroism spectra and high-level computations.

M3 - Artículo

SN - 1934-578X

VL - 7

SP - 735

EP - 738

JO - Natural Product Communications

JF - Natural Product Communications

ER -