Bioactive membranes of polymeric micro and nanocomposites prepared with the natural anionic marine polysaccharide (Alginate) functionalized with extracts of cat’s claw (uncaria tomentosa) and aloe vera

Suyeon Kim, Mariela Elgegren, Alonso Donayre, Betty Galaretta, Javier Nakamatsu

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

In this research, the nanostructured alginate (AL) membranes were prepared with natural bioactive compound, Cat's claw (Uncaria tomentosa) extract (UT). UT is broadly used as an anti-inflammatory agent and the effect on the treatment of Rheumatism was proved by many scientists. For this reason, we added this bioactive compound in the process of AL membrane formulation to improve the biological activities. 2-dimentional (2-D) and 3-dimentional (3-D) AL membranes were prepared with and without addition of UT extracts. 3-D AL membranes were prepared using ultrasound with high intensity. The wettability of AL membranes depending on the concentration of AL was studied by measuring contact angle and surface energy. Stabilization agent, poloxamer 407, was used to improve the stability of AL nanoemulsion. The effects of UT in 3-D AL membranes were studied by measuring swelling behavior and contact angle. The surface morphology was measured with scanning electron microscopy (SEM). Comparing to 2-D AL membranes, 3-D AL membranes presented rougher surface due to AL nanoparticles presence. When UT was incorporated in AL membranes, strong antioxidant activity and higher contact angle and swelling ratio were observed than non-UT incorporated AL membranes.

Original languageEnglish
Title of host publicationAdvanced Materials and Application III
EditorsMosbeh Kaloop
PublisherTrans Tech Publications Ltd
Pages131-136
Number of pages6
ISBN (Print)9783035716801
DOIs
StatePublished - 2020
Event3rd International Symposium on Advanced Materials and Application, ISAMA 2020 - Seoul, Korea, Republic of
Duration: 14 Feb 202016 Feb 2020

Publication series

NameMaterials Science Forum
Volume1007 MSF
ISSN (Print)0255-5476
ISSN (Electronic)1662-9752

Conference

Conference3rd International Symposium on Advanced Materials and Application, ISAMA 2020
Country/TerritoryKorea, Republic of
CitySeoul
Period14/02/2016/02/20

Keywords

  • Alginate
  • Anti-inflammatory activity
  • Antioxidant activity
  • Biodegradable
  • Uncaria tomentose

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