Best practice recommendations for the implementation of a digital pathology workflow in the anatomic pathology laboratory by the european society of digital and integrative pathology (ESDIP)

Filippo Fraggetta; Vincenzo L’imperio; David Ameisen; Rita Carvalho; Sabine Leh; Tim Rasmus Kiehl; Mircea Serbanescu; Daniel Racoceanu; Vincenzo Della Mea; Antonio Polonia; Norman Zerbe; Catarina Eloy

doi:10.3390/diagnostics11112167

Best practice recommendations for the implementation of a digital pathology workflow in the anatomic pathology laboratory by the european society of digital and integrative pathology (ESDIP)

Filippo Fraggetta, Vincenzo L’imperio, David Ameisen, Rita Carvalho, Sabine Leh, Tim Rasmus Kiehl, Mircea Serbanescu, Daniel Racoceanu, Vincenzo Della Mea, Antonio Polonia, Norman Zerbe, Catarina Eloy

Research output: Contribution to journal › Article › peer-review

67 Scopus citations

Abstract

The interest in implementing digital pathology (DP) workflows to obtain whole slide image (WSI) files for diagnostic purposes has increased in the last few years. The increasing performance of technical components and the Food and Drug Administration (FDA) approval of systems for primary diagnosis led to increased interest in applying DP workflows. However, despite this revolutionary transition, real world data suggest that a fully digital approach to the histological workflow has been implemented in only a minority of pathology laboratories. The objective of this study is to facilitate the implementation of DP workflows in pathology laboratories, helping those involved in this process of transformation to identify: a) the scope and the boundaries of the DP transformation; b) how to introduce automation to reduce errors; c) how to introduce appropriate quality control to guarantee the safety of the process and d) the hardware and software needed to implement DP systems inside the pathology laboratory. The European Society of Digital and Integrative Pathology (ESDIP) provided consensus-based recommendations developed through discussion among members of the Scientific Committee. The recommendations are thus based on the expertise of the panel members and on the agreement obtained after virtual meetings. Prior to publication, the recommendations were reviewed by members of the ESDIP Board. The recommendations comprehensively cover every step of the implementation of the digital workflow in the anatomic pathology department, emphasizing the importance of interoperability, automation and tracking of the entire process before the introduction of a scanning facility. Compared to the available national and international guidelines, the present document represents a practical, handy reference for the correct implementation of the digital workflow in Europe.

Original language	English
Article number	2167
Journal	Diagnostics
Volume	11
Issue number	11
DOIs	https://doi.org/10.3390/diagnostics11112167
State	Published - Nov 2021
Externally published	Yes

Keywords

Anatomic pathology workflow
Digital pathology
Laboratory information system
Whole slide imaging

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10.3390/diagnostics11112167

Cite this

Fraggetta, F., L’imperio, V., Ameisen, D., Carvalho, R., Leh, S., Kiehl, T. R., Serbanescu, M., Racoceanu, D., Mea, V. D., Polonia, A., Zerbe, N., & Eloy, C. (2021). Best practice recommendations for the implementation of a digital pathology workflow in the anatomic pathology laboratory by the european society of digital and integrative pathology (ESDIP). Diagnostics, 11(11), Article 2167. https://doi.org/10.3390/diagnostics11112167

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title = "Best practice recommendations for the implementation of a digital pathology workflow in the anatomic pathology laboratory by the european society of digital and integrative pathology (ESDIP)",

abstract = "The interest in implementing digital pathology (DP) workflows to obtain whole slide image (WSI) files for diagnostic purposes has increased in the last few years. The increasing performance of technical components and the Food and Drug Administration (FDA) approval of systems for primary diagnosis led to increased interest in applying DP workflows. However, despite this revolutionary transition, real world data suggest that a fully digital approach to the histological workflow has been implemented in only a minority of pathology laboratories. The objective of this study is to facilitate the implementation of DP workflows in pathology laboratories, helping those involved in this process of transformation to identify: a) the scope and the boundaries of the DP transformation; b) how to introduce automation to reduce errors; c) how to introduce appropriate quality control to guarantee the safety of the process and d) the hardware and software needed to implement DP systems inside the pathology laboratory. The European Society of Digital and Integrative Pathology (ESDIP) provided consensus-based recommendations developed through discussion among members of the Scientific Committee. The recommendations are thus based on the expertise of the panel members and on the agreement obtained after virtual meetings. Prior to publication, the recommendations were reviewed by members of the ESDIP Board. The recommendations comprehensively cover every step of the implementation of the digital workflow in the anatomic pathology department, emphasizing the importance of interoperability, automation and tracking of the entire process before the introduction of a scanning facility. Compared to the available national and international guidelines, the present document represents a practical, handy reference for the correct implementation of the digital workflow in Europe.",

keywords = "Anatomic pathology workflow, Digital pathology, Laboratory information system, Whole slide imaging",

author = "Filippo Fraggetta and Vincenzo L{\textquoteright}imperio and David Ameisen and Rita Carvalho and Sabine Leh and Kiehl, {Tim Rasmus} and Mircea Serbanescu and Daniel Racoceanu and Mea, {Vincenzo Della} and Antonio Polonia and Norman Zerbe and Catarina Eloy",

note = "Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2021",

month = nov,

doi = "10.3390/diagnostics11112167",

language = "English",

volume = "11",

journal = "Diagnostics",

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Fraggetta, F, L’imperio, V, Ameisen, D, Carvalho, R, Leh, S, Kiehl, TR, Serbanescu, M, Racoceanu, D, Mea, VD, Polonia, A, Zerbe, N & Eloy, C 2021, 'Best practice recommendations for the implementation of a digital pathology workflow in the anatomic pathology laboratory by the european society of digital and integrative pathology (ESDIP)', Diagnostics, vol. 11, no. 11, 2167. https://doi.org/10.3390/diagnostics11112167

Best practice recommendations for the implementation of a digital pathology workflow in the anatomic pathology laboratory by the european society of digital and integrative pathology (ESDIP). / Fraggetta, Filippo; L’imperio, Vincenzo; Ameisen, David et al.
In: Diagnostics, Vol. 11, No. 11, 2167, 11.2021.

Research output: Contribution to journal › Article › peer-review

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T1 - Best practice recommendations for the implementation of a digital pathology workflow in the anatomic pathology laboratory by the european society of digital and integrative pathology (ESDIP)

AU - Fraggetta, Filippo

AU - L’imperio, Vincenzo

AU - Ameisen, David

AU - Carvalho, Rita

AU - Leh, Sabine

AU - Kiehl, Tim Rasmus

AU - Serbanescu, Mircea

AU - Racoceanu, Daniel

AU - Mea, Vincenzo Della

AU - Polonia, Antonio

AU - Zerbe, Norman

AU - Eloy, Catarina

PY - 2021/11

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AB - The interest in implementing digital pathology (DP) workflows to obtain whole slide image (WSI) files for diagnostic purposes has increased in the last few years. The increasing performance of technical components and the Food and Drug Administration (FDA) approval of systems for primary diagnosis led to increased interest in applying DP workflows. However, despite this revolutionary transition, real world data suggest that a fully digital approach to the histological workflow has been implemented in only a minority of pathology laboratories. The objective of this study is to facilitate the implementation of DP workflows in pathology laboratories, helping those involved in this process of transformation to identify: a) the scope and the boundaries of the DP transformation; b) how to introduce automation to reduce errors; c) how to introduce appropriate quality control to guarantee the safety of the process and d) the hardware and software needed to implement DP systems inside the pathology laboratory. The European Society of Digital and Integrative Pathology (ESDIP) provided consensus-based recommendations developed through discussion among members of the Scientific Committee. The recommendations are thus based on the expertise of the panel members and on the agreement obtained after virtual meetings. Prior to publication, the recommendations were reviewed by members of the ESDIP Board. The recommendations comprehensively cover every step of the implementation of the digital workflow in the anatomic pathology department, emphasizing the importance of interoperability, automation and tracking of the entire process before the introduction of a scanning facility. Compared to the available national and international guidelines, the present document represents a practical, handy reference for the correct implementation of the digital workflow in Europe.

KW - Anatomic pathology workflow

KW - Digital pathology

KW - Laboratory information system

KW - Whole slide imaging

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M1 - 2167

ER -

Best practice recommendations for the implementation of a digital pathology workflow in the anatomic pathology laboratory by the european society of digital and integrative pathology (ESDIP)

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Keywords

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