Automatic working area classification in peripheral blood smears without cell central zone extraction

W. Xiong, J. H. Lim, S. H. Ong, N. N. Tung, J. Liu, D. Racoceanu, K. Tan, A. Chong, K. Foong

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

5 Scopus citations

Abstract

In this paper we study automatic classification of working areas in peripheral blood smears using image analysis and recognition methods. Such automatic classification can provide objective and reproducible quality control for the evaluation of smears and smear maker devices. However, research in this filed has drawn little attention. Existing methods either can not differentiate correctly different cell distributions or rely on the extraction of the central pallor zones in cells for counting, which are not always observable. In contrast, we do not rely on the pallor zone extraction thus on more general basis. We introduce two generic parameters to measure the goodness of working areas, one for the degree of overlap, and the other for the spatial occupancy. We also propose a cascading classification network for the classification of different areas. The effectiveness of our method has been tested on over 150 labeled images acquired from three malaria-infected Giemsa-stained blood smears using an oil immersion 100x objective.

Original languageEnglish
Title of host publicationProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
PublisherIEEE Computer Society
Pages4074-4077
Number of pages4
ISBN (Print)9781424418152
DOIs
StatePublished - 2008
Externally publishedYes
Event30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - Vancouver, BC, Canada
Duration: 20 Aug 200825 Aug 2008

Publication series

NameProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"

Conference

Conference30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
Country/TerritoryCanada
CityVancouver, BC
Period20/08/0825/08/08

Keywords

  • Central pallor zone
  • Classification
  • Distribution
  • Equivalent diameter
  • Generic features
  • Occupancy
  • Overlap
  • Peripheral blood smears
  • Working area

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