Atmospheric Pressure Femtosecond Laser Imaging Mass Spectrometry

Yves Coello; Tissa C. Gunaratne; Marcos Dantus

doi:10.1117/12.808252

Atmospheric Pressure Femtosecond Laser Imaging Mass Spectrometry

Yves Coello
, Tissa C. Gunaratne
, Marcos Dantus

Michigan State University

Research output: Contribution to journal › Conference article › peer-review

3 Scopus citations

Abstract

We present a novel imaging mass spectrometry technique that uses femtosecond laser pulses to directly ionize the sample. The method offers significant advantages over current techniques by eliminating the need of a laser-absorbing sample matrix, being suitable for atmospheric pressure sampling, and by providing 10μ m resolution, as demonstrated here with a chemical image of vegetable cell walls.

Original language	English
Article number	71821W
Journal	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	7182
DOIs	https://doi.org/10.1117/12.808252
State	Published - 2009
Externally published	Yes
Event	Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VII - San Jose, CA, United States Duration: 26 Jan 2009 → 28 Jan 2009

Keywords

Femtosecond laser
Imaging mass spectrometry
Microscopy
Ultrafast optics

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10.1117/12.808252

Cite this

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title = "Atmospheric Pressure Femtosecond Laser Imaging Mass Spectrometry",

abstract = "We present a novel imaging mass spectrometry technique that uses femtosecond laser pulses to directly ionize the sample. The method offers significant advantages over current techniques by eliminating the need of a laser-absorbing sample matrix, being suitable for atmospheric pressure sampling, and by providing 10μ m resolution, as demonstrated here with a chemical image of vegetable cell walls.",

keywords = "Femtosecond laser, Imaging mass spectrometry, Microscopy, Ultrafast optics",

author = "Yves Coello and Gunaratne, \{Tissa C.\} and Marcos Dantus",

year = "2009",

doi = "10.1117/12.808252",

language = "English",

volume = "7182",

journal = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

issn = "1605-7422",

note = "Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VII ; Conference date: 26-01-2009 Through 28-01-2009",

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TY - JOUR

T1 - Atmospheric Pressure Femtosecond Laser Imaging Mass Spectrometry

AU - Coello, Yves

AU - Gunaratne, Tissa C.

AU - Dantus, Marcos

PY - 2009

Y1 - 2009

N2 - We present a novel imaging mass spectrometry technique that uses femtosecond laser pulses to directly ionize the sample. The method offers significant advantages over current techniques by eliminating the need of a laser-absorbing sample matrix, being suitable for atmospheric pressure sampling, and by providing 10μ m resolution, as demonstrated here with a chemical image of vegetable cell walls.

AB - We present a novel imaging mass spectrometry technique that uses femtosecond laser pulses to directly ionize the sample. The method offers significant advantages over current techniques by eliminating the need of a laser-absorbing sample matrix, being suitable for atmospheric pressure sampling, and by providing 10μ m resolution, as demonstrated here with a chemical image of vegetable cell walls.

KW - Femtosecond laser

KW - Imaging mass spectrometry

KW - Microscopy

KW - Ultrafast optics

UR - https://www.scopus.com/pages/publications/65949115707

U2 - 10.1117/12.808252

DO - 10.1117/12.808252

M3 - Conference article

AN - SCOPUS:65949115707

SN - 1605-7422

VL - 7182

JO - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

JF - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

M1 - 71821W

T2 - Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VII

Y2 - 26 January 2009 through 28 January 2009

ER -

Atmospheric Pressure Femtosecond Laser Imaging Mass Spectrometry

Abstract

Keywords

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