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Item type:Publication, Tailoring size and release kinetics of κ/ι-hybrid carrageenan microgels via a surfactant-assisted technique(Taylor & Francis, 2020-01-25)κ/ι-Hybrid carrageenan microgels were prepared to be used as drug delivery systems. A surfactant-assisted microemulsion technique was used. Tween® 80 was used as surfactant and enrofloxacin was used as a model drug. The results showed that the amount of surfactant used during processing determines the size of the microgels as well as the amount of enrofloxacin that can be loaded. At low surfactant content, the initial burst release effect is dominant whereas at high surfactant content the burst release effect is negligible and the Fickian diffusion mechanism is dominant. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Synthesis, characteristics, and applications of modified starch nanoparticles: a review(Elsevier, 2021-12-02)2 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Recent Trends and Notable Advances of Alginate-Based Nano-Particles for Effective Biomedical Materials: Wound Healing and Drug Delivery(Trans Tech Publications Ltd, 2023-01-01)Alginate is natural biodegradable polymers often used for wound treatments and drug delivery purposes. Due to the structural characteristics, alginate polymers are able to form hydrogel. Alginate nanoparticles are obtained by diverse methodologies and the physical and chemical properties can be affected by production techniques and the molecules incorporated. Alginate possesses unique bioactivities such as biocompatibility, biodegradability, hydrophilicity and nontoxicity, so it has great potential for biomedical applications. Alginate based hydrogels and nanoparticles carrying active compounds are able to supply the optimal environments for wound healing and controlled drug administration including targeted or localized drug-delivery systems. In this review, the recent researches about the alginate and alginate-complex nanoparticles as potential tools for wound dressing membrane and drug delivery carriers are studied.2 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, DFT Assessments of BN, AlN, and GaN Decorated Carbon Cage Scaffolds for Sensing the Thiamazole Drug(Elsevier Ltd, 2023-05-01)Sensing drug substances by nanostructures are very important in accordance with the management of targeted drug delivery processes and drug substances detections. Boron nitride (BN), aluminum nitride (AlN), and gallium nitride (GaN) decorated carbon cage (BN-C, AlN-C, and GaN-C) scaffolds were assessed towards sensing the thiamazole (TMZ) drug through the wB97XD/6–31 + G* level of density functional theory (DFT) computations. The singular models were optimized and their combinations to each other were stabilized to obtain the interacting TMZ@Scaffold bimolecular complexes and their corresponding features. The results indicated the existence of non-covalent physical interactions between the substances and their electronic features indicated possibility of sensing function for the investigated scaffolds. Based on the variations of values of adsorption energy and energy gap, the features of recovery time and conductance rate were achieved to predict a sensing function for the models; TMZ@GaN-C was found at the highest suitability in comparison with TMZ@AlN-C and TMZ@BN-C models. The obtained thermochemistry results indicated a spontaneous process for the formation of TMZ@Scaffold complexes. Based on all the obtained results, an order of TMZ@GaN-C > TMZ@AlN-C > TMZ@BN-C was found for describing stability, formation, and electronic features suitability by assigning specific features for each of the singular BN-C, AlN-C, and GaN-C scaffolds towards the TMZ drug. As a consequence, two purposes of detections and adsorptions were approached for the investigated scaffolds to develop sensing functions of BN-C, AlN-C, and GaN-C scaffolds for the TMZ drug. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Carbon Quantum Dots Based on Marine Polysaccharides: Types, Synthesis, and Applications(Multidisciplinary Digital Publishing Institute (MDPI), 2023-06-01)The marine environment offers a vast array of resources, including plants, animals, and microorganisms, that can be utilized to extract polysaccharides such as alginate, carrageenan, chitin, chitosan, agarose, ulvan, porphyra, and many more. These polysaccharides found in marine environments can serve as carbon-rich precursors for synthesizing carbon quantum dots (CQDs). Marine polysaccharides have a distinct advantage over other CQD precursors because they contain multiple heteroatoms, including nitrogen (N), sulfur (S), and oxygen (O). The surface of CQDs can be naturally doped, reducing the need for excessive use of chemical reagents and promoting green methods. The present review highlights the processing methods used to synthesize CQDs from marine polysaccharide precursors. These can be classified according to their biological origin as being derived from algae, crustaceans, or fish. CQDs can be synthesized to exhibit exceptional optical properties, including high fluorescence emission, absorbance, quenching, and quantum yield. CQDs’ structural, morphological, and optical properties can be adjusted by utilizing multi-heteroatom precursors. Moreover, owing to their biocompatibility and low toxicity, CQDs obtained from marine polysaccharides have potential applications in various fields, including biomedicine (e.g., drug delivery, bioimaging, and biosensing), photocatalysis, water quality monitoring, and the food industry. Using marine polysaccharides to produce carbon quantum dots (CQDs) enables the transformation of renewable sources into a cutting-edge technological product. This review can provide fundamental insights for the development of novel nanomaterials derived from natural marine sources. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Highly Efficient Ultrasound-Assisted Anthocyanin Extraction for Colorimetric Sensors and Drug Delivery Systems in Wound Dressings(Springer Science and Business Media Deutschland GmbH, 2025)Anthocyanins were extracted from Peruvian purple cabbage (PC) using ultrasonication, a greener and more efficient technique. The anthocyanin extract was incorporated into polymeric alginate membranes to obtain a pH-sensitive biosensor to monitor wound healing processes and drug delivery. The halochromic behavior was tested in five different acidic media (pH 4, 5, 6, 7, and 8) giving a differential colour for each. The antioxidant capacity of the PC extract was evaluated using the ABTS discoloration assay. A 1% (w/v) solution of the lyophilized extract resulted in 55.17 ± 0.46 TEAC mg/g. Phenolic content and equivalents of cyanidin-3-glucoside were evaluated using the Folin-Ciocalteu and pH differential assays, respectively, resulting in 36.1 ± 0.55 GAE mg and 8.63 ± 0.54 of C-3-G mg per gram of lyophilized extract, respectively. Finally, the PC extract was embedded in alginate (AL) membranes and characterized by contact angle and transparency.5